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Hemophilia Foundation of Michigan Patient Choice PolicyAs approved by the Board of Directors September, 2001The Hemophilia Foundation of Michigan is committed to the promotion and protection of patient choice of medical care provider, medical treatment, blood products and home infusion therapy services. To promote informed choice, HFM will provide programs and services to educate families about quality of care issues, treatment and care options, blood product safety, the cost of treatment and any other issues that may impact patient decision-making. The information on this page is for your general use only. HFM does not provide medical advice, treatment, or legal advice or engage in the practice of medicine. HFM under no circumstance recommends particular treatments for specific individuals. HFM strongly recommends you consult your physician or treatment centers before pursuing any course of treatment.Product Information
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| I. RECOMBINANT FACTOR PRODUCTS | ||||
| A. Recombinant Factor VIII (Hemophilia A) | ||||
| Product | Distributor/ Manufacturer | Contact Information | Generation | Human/Animal Protein used in Culture Medium |
| Advate | Baxter | 800-423-2090 www.hemophiliagalaxy.com | Third | None |
| Helixate FS | ZLB Behring (manufactured by Bayer) | 800-683-1288 www.zlbbehring.com | Second | Human plasma protein |
| Kogenate | Bayer | 800-243-4153 www.hemophiliabayer.com | Second | Human plasma protein |
| Recombinate | Baxter | 800-423-2090 www.hemophiliagalaxy.com | First | Bovine serum albumin/human albumin stabilizer |
| Refacto | Wyeth | 888-999-2349 www.hemophiliavillage.com | Second | Human serum albumin |
| B. Recombinant Factor IX (Hemophilia B) | ||||
| BeneFIX | Wyeth | 888-999-2349 www.hemophiliavillage.com | Third | None |
| C. Recombinant Factor VII A | ||||
| NovoSeven | NovoNordisk | 800-727-6500 www.novonordisk-usa.com | Second | Bovine calf serum |
| II. FACTOR PRODUCTS DERIVED FROM HUMAN PLASMA | |||
| A. Purified Factor VIII (Hemophilia A) | |||
| Product | Distributor/ Manufacturer | Contact Information | Other |
| Hemofil-M | Baxter | 800-423-2090 www.hemophiliagalaxy.com | |
| Monarc-M | American Red Cross (manufactured by Baxter using ARC plasma) | 202-303-4498 www.redcross.org | |
| Monoclate-P | ZLB Behring | 800-683-1288 www.zlbbehring.com | |
| B. Purified Factor VIII Products That Contain von Willebrand Factor | (FDA Approval) | ||
| Alphanate | Grifols | 800-421-0008 www.grifols.com | Pending |
| Humate P | ZLB Behring | 800-683-1288 www.zlbbehring.com | Yes |
| Koate DVI | Bayer | 800-243-4153 www.hemophiliabayer.com | No |
| C. Purified Factor IX (Hemophilia B) | |||
| AlphaNine SD | Grifols | 800-421-0008 www.grifols.com | |
| Mononine | ZLB Behring | 800-683-1288 www.zlbbehring.com | |
| D.Prothrombin Complex Concentrates (Deficiencies of Factors II, VII, X, also contains FIX | |||
| Bebulin VH | Baxter | 800-423-2090 www.hemophiliagalaxy.com | |
| Profilnine SD | Grifols | 800-421-0008 www.grifols.com | |
| Proplex-T | Baxter | 800-423-2090 www.hemophiliagalaxy.com | |
| III. ANTI-INHIBITOR COAGULATION COMPLEX PRODUCTS | ||||
| Product | Distributor/M anufacturer | Contact Information | Plasma Type | Inhibitor Type |
| Autoplex T | NABI (manufactured by Baxter) | www.nabi.com | Human | Factor VIII or IX |
| FEIBA VH | Baxter | 800-423-2090 www.hemophiliagalaxy.com | Human | Factor VIII or IX |
| Hyate C | Ipsen, Inc. | 800-456-7322 www.hyate.com | Porcine | Factor VIII |
| IV. DESMOPRESSIN PRODUCTS (von Willebrand Disease) | |||
| Product | U.S. Distributor | Contact Information | Manufacturer |
| DDAVP Injection | Aventis Pharma | 800-683-1288 www.zlbbehring.com | Ferring |
| Stimate Nasal Spray | ZLB Behring | 800-683-1288 www.zlbbehring.com | Ferring |
Adapted from recommendations made by the Medical and Scientific Advisory Committee (MASAC) and adopted by the NHF Board of Directors on November 9, 2003. Product information is for your general information only. HFM does not engage in the practice of medicine and will not recommend particular products or treatments. In all medical decision-making, you should consult with your physician or your hemophilia treatment center.
- DOWNLOAD the TEXT of MASAC (PDF - 253kb, 13 pages with glossary)
- DOWNLOAD the TABLES of MASAC (PDF - 208kb, 11 pages)
- MASAC Recommendations Concerning the Treatment of Hemophilia and other Bleeding Disorders can also be found on the National Hemophilia Foundation website.
- Download Region V-East facility information.
- Query CDC listing of Comprehensive Hemophilia Treatment Centers.

